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Most Innovative Companies

Amgen

Amgen is one of the world's largest biotechnology companies, generating nearly $23 billion in annual revenue and employing some 19,000 thousand people worldwide. The company, founded in 1980, has a relatively small but profitable portfolio of drugs—led by Enbrel, for treatment of rheumatoid arthritis, and Neulasta, used to prevent infections during chemotherapy. In May 2018, the FDA approved Aimovig, a drug co-developed by Amgen and Novartis that's the first FDA-approved preventive migraine treatment in a new class of drugs that use engineered antibodies to target specific protein receptors. Once-a-month treatments of Aimovig, with its EpiPen-like injector, block receptors for a protein called CGRP and are consistently shown to reduce monthly migraine days, with many patients achieving at least a 50% reduction and fewer side effects than existing migraine medications.

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2019: Biotech
2011: Biotech
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headquarters: Thousand Oaks, CA
Amgen On The Web
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