How Probiotics Can Help Reduce The Use Of Antibiotics On Farms

Food brands want to eliminate the overuse of antibiotics in livestock–and healthy bacteria could help fill the gap.

How Probiotics Can Help Reduce The Use Of Antibiotics On Farms
Probiotics for livestock is moving beyond its snake oil reputation. [Top Photo: Flickr user Brian Lauer]

With food chains like Subway, Chipotle, Panera, Chick-fil-A and McDonald’s all now committing to use antibiotic-free chicken, there’s pressure on chicken producers to find alternatives to antibiotics for disease prevention and growth promotion.


That, in turn, is an opportunity for companies like Novozymes. A Danish chemical giant with a long history producing and developing new enzymes, Novozymes is working on probiotic treatments for poultry–one of several promising non-antibiotic technologies being explored by scientists. Probiotics are good bacteria that promote animal (or human) gut health. They can be added to feeds to improve livestocks’ resistance to pathogenic bacteria and potentially–like antibiotics–may promote growth.

USDA Flickr

Some farmers already use probiotic supplements in their feeds. But Novozymes thinks there’s now an opportunity to expand the market and establish more scientific rigor in the field. Like probiotic human foods, the effectiveness of these treatments is sometimes questioned by scientists (and farmers).

Helle Warrer Poulsen, the company’s vice president for animal health and nutrition, says while probiotics have attracted “true believers” in the industry, there’s still a snake-oil reputation to them. “There is a need and potential to expand the category of microbial solutions by bringing in more science to understand why it works, and under what circumstances,” she says. “This is a pretty rational industry.”

Novozymes has bought one probiotic producer based in Arkansas. It makes products for poultry hatcheries mainly. And it’s formed a research alliance with Adisseo, a French producer of animal food additives. The groups plan to release their first bacteria-based product in the next six months. DuPont and Calpis are also offering probiotic treatments.

Flickr user David Blaine

In going “antibiotic free,” retailers and producers normally agree to stop using the drugs for growth promotion–that is, as a normal part of what they feed their animals–but they still may use drugs to treat actual diseases. The probiotics are a form of prevention, hopefully limiting the need for drug delivery both preemptively and after an animal gets sick. The most important animal antibiotics to eliminate are those also used to treat human diseases–that’s how antibiotic-resistant pathogens can come about.

Probiotics aren’t the only antibiotic alternative. Others include antibacterial vaccines, bacteriophages (viruses that kill bacteria), peptides, and plant extracts. These solutions also show promise in reducing the need for antibiotics and, perhaps, eventually in replacing them, although that may take some time yet.


One recent journal review notes there’s still a “considerable gap” between what’s needed for antibiotic alternatives and what’s available right now. Moreover, there’s no guarantee the alternatives won’t promote drug resistance themselves. Scientists only discovered penicillin-resistance once penicillin was in heavy use, the paper points out.

In the meantime, the best we can do is use antibiotics more carefully, limiting their use on farms, while preserving their value for humans. Aside from antimicrobial resistance, there are other reasons to get away from indiscriminately using antibiotics as growth promoters. Since limiting antibiotic use, Europe has improved how it treats its livestock, the paper says.

About the author

Ben Schiller is a New York staff writer for Fast Company. Previously, he edited a European management magazine and was a reporter in San Francisco, Prague, and Brussels.