Amy Pascal has an uncanny knack for predicting the next big thing. To wit: Pascal gambled $60 million on Michael Jackson's raw rehearsal footage shortly after his death, and turned it into $260 million in box-office receipts. She's green-lighted films--including the Spider-Man franchise, Zero Dark Thirty, and Cloudy With a Chance of Meatballs, that have helped the studio hit new box-office records. Under her leadership, 89 Sony Pictures movies hit #1 at the domestic box office, more than any other studio. She's also co-chairman of Sony Pictures Entertainment, whose television hits have included The Dr. Oz Show, Breaking Bad, Masters of Sex, and Shark Tank.